Oncotarget helps resolve controversy over the role of FOXO genes in breast cancer

Cancer is caused by a change in the genes the regulate cell death. In theory, a cancer cell could live forever, although the tendency of the disease to kill the patient if unchecked prevents this from happening. No one knows what causes the cells to mutate, although scientists know that a genetic factor makes it more likely that some people will develop breast caner. The family involvement has been known, and both women and men with a history of breast cancer in their family can develop the disease. Researchers at Oncotarget continue to work out the role of four genes that belong to the FOX group, according to the online journal Research Gate.

Four of the FOXO genes – 1, 3, 4 and 6 – are known to play a role in carcinogenesis and apoptosis of breast cancer. The state of research so far has researchers arguing over which process on which the genes have impact. A few braver researchers argue that the genes can effect both, depending on how they are expressed in an individual. Oncotarget researchers hope further researcher will resolve the debate and the mystery surrounding the functions of these genes. Check Oncotarget journal at scimagojr.com

Someone who has been newly diagnosed with breast cancer may come upon these genes and their disputed function eventually, but the best course of action is still routine screenings to detect the formation of the disease early. This can be done through self examination and regular mammograms. Regular mammograms should start after a woman turns 40, and they should be conducted every two years. Self-examinations should be performed on a more regular basis. Every two months is generally recommended, but this can be done less or more often as desired.

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